Code and results for the 2025 Adaptyv Bio Adaptyv Nipah Binder Competition
Our three person team made the following final submissions:
- Tapan Ravi: BindCraft (Proteinbase, details)
- Bryce Johnson: BindCraft plus a supervised model trained on ESM-C embeddings (Proteinbase, details)
- Anthony Gitter: Kosmos AI scientist (Proteinbase, details)
- PDB 2VSM: provided by Adaptyv, Nipah virus attachment glycoprotein in complex with human cell surface receptor ephrinB2
- University of Oxford’s ChAdOx1 NipahB vaccine candidate: need to find sequence and details, check relevance to target
- MBP1F5: need to find sequence and details, check relevance to target
- rVSV-Nipah vaccine candidate: need to find sequence and details, is it the same as clinical trial NCT05178901 because that is likely irrelevant
- Nipah virus vaccine candidate (HeV-sG-V): need to find sequence and details, aka HenipaVaxTM, check clinical trial NCT04199169
- nAH1.3: possibly other relevant information, check full paper
- Adaptyv added a list to the competition FAQ: m102.4 (anti-G glycoprotein), 1F5 / hu1F5 / MBP1F5 (anti-F glycoprotein), and mAb92.